Геронтология и гериатрические исследования

Абстрактный

The Relationship between IL-1? Gene Polymorphisms and Coronary Artery Disease in Elderly Population

Jiayi G, Zhengxia L and Xiang L

Coronary Artery Disease (CAD) is the leading cause of morbidity and death in people around the world. In recent years, many studies have shown that cytokine gene polymorphism can change protein expression and protein function, thereby affecting their role in CAD. Interleukin (IL)-1β is a classical inflammatory factor, and the gene mutation of IL-1β plays a very important role in the occurrence and development of CAD. In this paper, the relationship between IL-1β gene polymorphism and CAD reported in the past will be collected and briefly summarized. It is expected that these results can provide a reference for the early diagnosis and treatment of CAD.