Jangala Chesonbabu, Navuru Spandana and Aruna Lakshmi K.
Hydroxychavicol isolated from Piper betle leaves showed inhibitory activity against gastrointestinal pathogens. It demonstrated inhibitory effect on all gastrointestinal pathogens tested (MIC 200-400 μg/mL) with MBC that was twice the inhibitory concentration. Hydroxychavicol demonstrated concentration-dependent killing of Staphylococcus aureus and Escherichia coli up to 4 x MIC, suggesting that hydroxychavicol may be a useful compound for the development of antibacterial agents against gastrointestinal pathogens and has great potential for use in the treatment of gastrointestinal infections.