Фармацевтика Аналитика Акта

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Spectroscopic Methods for Analysis of Nano Drug Distribution System

Hesham Salem, Fatma A. Abo Elsoud, Ahmed Magdy, Dina Heshmat, Ahmed Elkady, Kerolos Wissa, Kareem Hassan, Rania Abdelrady

The size of the objects that are constituted within an alleged nano metric measurement of 1 to 100 nm is generally the main feature of nanoscience and nanotechnology. The system of unharness may be an essential method of acknowledging contained drug delivery systems in the formation of nano drug. Nanoparticles may surpass the crucial troubles of traditional little molecules/biomacromolecules; such as protein, ribonucleic acid, and DNA; utilized in several diseases through permitting objective delivery and surpassing biological obstacles. Many spectroscopical analytical techniques were applied to define the free drug component from the nano drug formation, according various substantial cases, during various duration. One of them is the analytical chemistry which concerns with the development of new techniques to develop old ones and supply the requirements of chemical information constrained by modern issues. Analytical chemistry is greatly affected by the development of nanoscience and nanotechnology. The aim of this review is to present a comparison of different spectroscopic analytical techniques which are presently applied to various systems of nano drug delivery to present elaborated and helpful data for the other researchers.