Журнал тромбоза и кровообращения: открытый доступ

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Role of ABO Blood Groups as Risk Factor for IHD

Mohammad Mujtaba Ghaffari1, Abdul Samad Ahmadi, Aida Akhenbaeva, Kyat Biandivich Abzaliev

Background: Around the world, CAD is the leading cause of mortality. The Kazakhstan population has one of the most remarkable risks of IHD in the world. Observational studies on the association between ABO blood types and coronary artery disease risk must be examined.

Aim: The aim of the research is to find whether there is a link between the ABO blood group and IHD.

Methods: This is a descriptive, cross-sectional study carried out in “JSC hospital” during 2020. The research included patients who were hospitalized with an IHD diagnosis. Data were recorded and analyzed using SPSS 22. Association between blood group and IHD was analyzed using chi-square test and independent T-test for comparison of patients' age in both genders.

Results: During the one-year study, a total of 649 patients were enrolled. The patients' average age was 64.2 ± 9.238 and the frequency of participants was 232 (35.74%) females and 417 (64.25%) males. The distribution of blood group was as follows: Blood group O was 32.2%, A-31.43%, B-27.73%, AB-8.62%. Among these blood groups, blood group O was the common type of blood group (not significant), and AB was the least common. In the study population, there was no considerable variation in the prevalence of blood groups with IHD (p=0.108).

Conclusion: In this single hospital-based study, there was no significant connection between ABO blood types and ischemic heart disease (p=0.77).