Клиническая и медицинская биохимия

Абстрактный

Relation Between Red Cell Distribution Width and Serum Lipoprotein(a) in Healthy Adult Men

Ahmet Celik* and Metin Kilinc*

Objective: The aim of this study was to investigate the relationship between the serum lipoprotein(a) (Lp(a)) levels and red cell distribution width (RDW) in healthy adult men.

Method: For this purpose, 116 healthy, drug-free adult men with normal physical examination and laboratory findings were included in the study. Serum Lp(a) levels and RDW were measured by auto analyzers and commercial kits.

Results: The mean age of the subjects was 27.2 years, mean body mass index was 24.2, and mean serum Lp(a) level was 0.21 mg/dL. There was a significant positive correlation between the serum Lp(a) and RDW (r=0.267; p=0.004).

Conclusions: Of late, RDW is a commonly used marker for some diseases. High Lp(a) predicts the risk of cerebrovascular disease, atherosclerosis, thrombosis, and stroke. Evaluation of both Lp(a) and RDW may be useful to predict the risk for coronary heart disease, heart failure, hypertension, arrhythmias, and stroke in healthy subjects in the future.