Журнал бактериологии и паразитологии

Абстрактный

Recent advances in effective treatment of patients with multidrug-resistant tuberculosis (MDR-TB)

Suhail Ahmad

Tuberculosis (TB) is a major infectious disease worldwide. Most active TB cases in humans are caused by Mycobacterium tuberculosis [1]. Some cases in Africa are caused by Mycobacterium africanum, while Mycobacterium bovis can also cause TB in people who consume unpasteurized milk [1,2]. The global burden of TB remains enormous. According to the World Health Organization (WHO), there were about 10 million new cases of active TB and 1.451 million deaths in 2018, making TB one of the top 10 killers and the leading cause of death from a single infectious agent [3]. About 87% of TB cases occurred in 30 high TB ​​burden countries and two-thirds of all cases occurred in just eight countries (India, China, Indonesia, the Philippines, Pakistan, Nigeria, Bangladesh, and South Africa) [3]. Most cases of active TB in high TB ​​burden countries result from recent infection/reinfection, whereas in low TB burden countries they usually result from reactivation of latent infection acquired several years ago [2,4,5].