Журнал биомолекулярных исследований и терапии

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Prognostic Value of Proinflammatory Cytokines in Breast Cancer

Ahmed A. Al-Hassan, Batool H. Al-Ghurabi and Isam Hussain Al-Karkhi

Cytokines are factors that are known to have both tumor-promoting and inhibitory effects on breast cancer growth. Different cytokines play an important role in controlling the immune system. This study was carried out to investigate the alterations in serum levels of proinflammatory cytokines (IL-1α, IL-6 and TNF-α) in breast cancer patients, and its relation with progression of this cancer. The current results revealed that there is significant elevation in median serum levels of IL-1α, IL-6 and TNF-α, P