Журнал фармаконадзора

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Pharmacovigilance: A Meta-Analysis on ADRS of Past and Recent Tragedy Occurred in Gambia

Junaid Tantray, Mohd Zaid, Sourabh Kosey, Akhilesh Patel, Ashish K Sharma, Rajesh Sharma, Deepak Nathiya, R.P Singh , Nandini Kushwaha

Pharmacovigilance is a crucial component of clinical research and is studied in depth. They are the stage of pharmaceutical research that can relate to the detection, assessment, comprehension, and avoidance of hazardous effects, with an emphasis on both the long-term and short-term impacts of medication. The company initially produced common medications including paracetamol and riboflavin 5'-phosphate. Recently the tragedy has taken place in Gambia that has killed 66 innocent children’s by serving the cough syrup to child and the company from this has been made is Maiden pharmaceutical India. The cough syrup name that has been made is Promethazine Oral Solution, Kofexmalin Baby Cough Syrup, Makoff Baby Cough Syrup and MaGrip N Cold Syrup. In this the increase number of diethyl glycol and ethyl glycol in the solution that can cause renal and neurological damage. In past time many tragedies happened in world that is listed as: Tuskegee Syphilis study, Guatemala syphilis experiment, Thalidomide Tragedy, Clioquinol Tragedy, and Tragedy of Accutane. They have lack of concern for maintaining purity standards the vital roles performed by healthcare professionals, the pharmaceutical industry, the media, and WHO programmes. Regulatory relies on reporting of unfavorable drug reactions to ensure that medications are acceptable safe. Unfortunately, underreporting plagues all reporting systems. So, in India there is lack of regulatory rely are there which needs to be improved in future and more reporting programmes should be conducted to increase reporting of side effects.