Persistent Hypocalcemia in a Premature Neonate Exposed to Topiramate In-Utero

Roia Katebian, Pamela Nicoski, Katherine Katsivalis, Jonathan Muraskas*

Neonatal hypocalcemia can result from numerous etiologies and is commonly seen in premature neonates. We describe a late preterm neonate with asymptomatic hypocalcemia whose mother took topiramate throughout the entire pregnancy. Other factors that may contribute to hypocalcemia, including infant of a diabetic mother, were ruled out in our patient. The patient we are reporting on required calcium supplementation for persistent hypocalcemia most likely due to fetal topiramate exposure.