Журнал канцерогенеза и мутагенеза

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Organ Specific Killing of a Dispensable Organ or a Cell Population in an Organ-A Successful Design for Cancer Therapy-A Hypothesis

Håkan Olsson

Purpose: This article hypothesizes that designing cancer therapies based on the organ specific toxicity of the normal tissue of the organ from which the tumors originated could be worthwhile. A prerequisite for successful therapy is that the individual can recover from damage done to the organ or cells. Results: Therapeutic examples are given for lymphoma, kidney cancer, melanoma and leukemia.   Conclusion: Efforts should be made to identify new agents with organ specific toxicity and study their potential as a cancer therapy for the same organ.