Фармацевтика Аналитика Акта

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Non-Steroidal Anti-Inflammatory Drug (NSAID)-Induced Small Intestinal Injury

Akihiro Tajima

Non-steroidal anti-inflammatory drug (NSAID), including aspirin, induced small intestinal injuries are frequently seen in clinical field. Capsule endoscopy and double balloon endoscopy are major diagnostic methods. Small intestinal injury includes bleeding, erosion, and ulceration. Unfortunately, accurate mechanism(s) of NSAID-induced small intestinal injuries are remained to be determined so far. In terms of therapy, there are currently no therapies specifically designed or approved for the prevention of NSAID-induced enteropathy, although many medications are prescribed. Further clinical and basic researches are waiting.