Отчеты о случаях диабета

Абстрактный

Methylglyoxal as a Marker of NAFLD Severity in Patients with Type 2 Diabetes

LA Zvenigorodskaya*,MV Shinkin, AV Petrakov, TV Nilova

Glycation is due to the ability of glucose to form irreversible chemical compounds with amino groups of lysine and arginine - methylglyoxal (MG).

Methylglyoxal (MGO) is the natural compound with the recipe CH3C(O)CHO. It is a diminished subordinate of pyruvic corrosive. It is a responsive intensify that is embroiled in the science of diabetes. Methylglyoxal is delivered modernly by corruption of starches utilizing overexpressed methylglyoxal synthase.

Vaporous methylglyoxal has two carbonyl gatherings, an aldehyde and a ketone. Within the sight of water, it exists as hydrates and oligomers. The arrangement of these hydrates is demonstrative of the high reactivity of MGO, which is applicable to its organic conduct.