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Manifestations of Pregabalin Withdrawal

Alexandra Hamlyn, Kalvin Foo, Anum Bhatia and Bradford Bobrin

Pregabalin is an analog to isobutyl γ-aminobutyric acid (GABA), and is commonly utilized as an anticonvulsant and medication for neuropathic pain. Pregabalin withdrawal has not been well documented, but is commonly described as a constellation of symptoms including anxiety, tachycardia, diaphoresis, nausea, and aggression. We report a case of pregabalin withdrawal with a primary presentation of akathisia, which has yet to be described in current literature.