Биохимия и аналитическая биохимия

Абстрактный

In-vitro Anti-Cancer Activity of Extracts Dracaen Cinnabari Balf. F Resin from Socotra Island in Yemen Republic

Yasser Hussein Eissa Mohammed

Plants have a long history of use in treatment of cancer, Since many years, plants were known to possess anticancer activities against different cancer cell lines. In this paper, we report a study based on anticancer properties of Dragon cinnabari resin. The resin of plant material was collected, shade dried and extracted with different solvents using soxhlet extraction procedure. In vitro anticancer activity is assayed with standard MTT colorimetric procedure against MCF-7 cell line. From the analysis it was found that Ether and Ethyl acetate of dragon cinnabari Balf. f showed nearly 50% MCF-7 cell line inhibition at 100 µg/ml tested dose, whereas other extracts did not display much anticancer activities against MCF-7 breast cancer cell line. Based on the cytotoxicity studies against MCF-7 cell lines the ether and ethyl acetate extracts could be used as potential source for anticancer drugs.