Глобальный журнал биологии, сельского хозяйства и медицинских наук

Абстрактный

In vitro Antibacterial Potential of Rosa Damascena and Terminalia Chebula against Bacterial Peritonitis

Wagih A. El-Shouny, Sameh S. Ali & Alsayed M. Alnabarawy

Twenty two bacterial isolates were collected from hundred peritoneal samples taken from patients that were admitted to Tanta university hospital, Egypt. All the investigated isolates were identified morphologically and biochemically. The twenty two isolates were subjected to in vitro evaluation for antibiotic sensitivity test using antibiotics from different classes. Rosa damascena and Terminalia chebula were extracted using different solvents (Methanol and acetone) and were investigated for antibacterial activity against the 22 bacterial isolates. The sensitivity was determined using agar well diffusion method and the inhibition zones were compared with the standard drug gentamicin. The extracts showed a wide spectrum of inhibition against the tested isolates. Acetone extracts of the two plants were proven to have the strongest antibacterial activity than the methanol extracts. The minimum inhibitory concentrations of extracts were determined. GC-MS and FT-IR analyses were carried out for the T. chebula acetone extract as the best antibacterial agent.