Yujun Feng, Ming Cao, Zuowei Wu, Fuliang Chu, Ying Ma, Changjun Wang, Huimin Zhang, Xuzhen Pan, Xuhu Mao and Quanming Zou
Streptococcus suis (S. suis), a group of heterogeneous species with thirty-five serotypes, is considered a previously neglected but newly emerging human pathogen. The lack of a complete understanding of the molecular mechanism by which this group of pathogenic bacteria infects both pigs and humans has significantly hampered the availability of specific/effective therapeutics against severe S. suis infections. The publication of the first genomic sequence of S. suis has ushered in its “Omix era”. This review focuses on the recent highlights of S. suis research in Omix aspects. In addition, we discuss the remaining research gaps and future perspectives.