Журнал болезней крови и переливания крови

Абстрактный

Diverse Clinical manifestations in Sickle Cell Anemia: study in District Amravati, MS India.

Varsha Wankhade, Andhale RB and Sangita Lodha

Background of Study: Sickle cell anemic patients show diverse clinical symptoms with varied complications influenced by genetic, environmental and socioeconomic factors. Sickle cell anemia is prevalent in district Amravati, MS, India. In the present study, some symptomatic presentation of sickle cell anemic patients district Amravati, MS were studied in order to know pathophysiological complications going on in sickle cell anemia. In total, 67 sickle cell anemic patients were investigated. Information regarding some clinical symptoms was gathered from the patients and filled in the data sheets. It was observed that 77.77% patients frequently suffer from fever, 85.18% patients suffers from joint and chest pain, 81.48% experience recurrent tiredness, 85.18% experience shortness of breath, swelling of abdomen was found in 29.62% patients, 48.14% experience unusual headache. From the study of data sheet it was found that 29.62% sickle cell patients suffer from jaundice. In 51.85% patients, growth was delayed. Recurrent occurrence of pain episodes was observed in 55.55% patients. Thus sickle cell anemia in district Amravati shows variable clinical manifestations in variable percentage. Thus it is proposed to manage the disease properly as soon as it is detected.