Журнал исследований опухолей и отчетов

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Current Topics on Cancer Stem Cell Associated Melanoma Treatment Researches

Kubilay Doğan Kılıç, Hatice K Başaloğlu, Yiğit Uyanikgil and Mehmet Turgut

Malignant tumor of melanocytes describes as “melanoma”. Melanocytes are derived from the neural crest and make the pigment melanin [1]. Despite most melanomas emerge in the skin, they may arise on mucosal surfaces or eyes and rarely intestines. A common point of these organs is the migration of neural crest cells [2,3]. An expected 13.7 million Americans with cancer background were alive on 2012. In the same report, in 2022, it is expected that number will increase approximately 18 million. It makes melanoma the 3rd most prevalent cancers among males [4]. The risk factors are environmental factors, family history, characteristics of pigment, multiple nevi, immunosuppression and genetic factors