Журнал микробных и биохимических технологий

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Bacteriophage Genome Sequencing: A New Alternative to Understand Biochemical Interactions between Prokaryotic Cells and Phages

Marco Túlio Pardini G, Laís Silva B and Maryoris Elisa Soto L

Bacteriophages are viruses or semi-autonomous genetic entities that depend on prokaryotic cell’s metabolism to multiply. The use of lytic phages as biocontrol agents in many fields such as food preservation, disease control, agriculture production signifies the need of most appropriate and standard methods to insure application safety. Bacteriophage full genetic material sequencing is a new alternative to better understand phage encoded proteins and biomolecules (especially phage lytic enzymes) involved in the process of bacterial cell lysis and death. Thus, this short review aimed to discuss sequencing importance applied to bacteria-phage interactions in society commercial sectors, focusing in the food industry.