Здоровье полости рта и лечение зубов

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A Pilot Study Into the Effectiveness of Two Antimicrobial Mouthrinses in a Group of Russian Adults With Gingivitis

Edith Kouzmina, Oleg Yanuschevitch, Alla Lapatina, Tamara Smirnova, Irina Kuzmina

Aim: To evaluate the effectiveness of antimicrobial mouthrinses with chlorhexidine and essential oils for the improvement of oral hygiene and the reduction of gingival inflammation in patients with gingivitis and to reveal their influence on oral microflora. Methods: 86 adult patients (aged 20-35 years old) with chronic marginal gingivitis were randomly selected in three groups. Test group 1 used mouthrinse One Drop Only Ondrohexidine (One Drop Only GmbH, Germany), containing chlorhexidine digluconate (0.1%) and potassium fluoride (250 ppm). Test group 2 used Listerine Cool Mint (McNeil PPC, USA), containing thymol (0.064%), eucalyptol (0.092%), methyl salicylate (0.06%), and menthol (0.042). The control group just rinsed the oral cavity with water. Values of the Patient Hygiene Performance Index (PHP), Approximal Plaque Index (API), Gingival Index (GI), and Sulcular Bleeding Index (SBI) were assessed at baseline and after two, four, and six weeks. Evaluation of pathogenic and resident bacterial species concentration in gingival sulcus biofilm (by cultural bacteriological examination) was conducted at baseline and after six weeks. Results: Oral hygiene (toothbrushing and six-week mouthrinse application) led to a significant decrease in plaque accumulation on smooth (by 58.1 and 62.3% in test groups 1 and 2, respectively) and approximal (by 53.9 and 58.5% in test groups 1 and 2, respectively) tooth surfaces, reduction of gingival inflammation (by 69.0 and 71.6% in test groups 1 and 2, respectively) and gingival sulcus bleeding (by 80.6 and 82.3% in test groups 1 and 2, respectively). Final indices values in both test groups were significantly (P