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A Narrative Review on the Most Important Management of Keratocystic Odontogenic Tumor

Mehdi Azadi , Saeed Bashar, Narges Hajiani , Hooman Amiri, Zahra Ansari

Keratocystic odontogenic tumor (KCOT) is a benign neoplasm with a keratinized epithelial outline with a high recurrence rate. The treatment methods in KCOT are still debated. The aim of all treatment methods is to eradicate the cyst and to reduce recurrence and surgical complications. This review article was conducted to assess the findings of studies on the diagnosis, management and recurrence of KCOT. Methods: Information were gathered by searching keywords such as management, treatment, pharmacology, surgery and keratocystic odontogenic tumor in International databases such as Web of Science, PubMed and Scopus. The search period was between 2010 -2020. Results: The study showed that the site of KCOT was mostly affected in the mandible. Techniques used for treatment include decompression, marsupialization, enucleating with or without adjunct, Caldwell-LUC surgery and resection. Of the 40 studies, recurrence was observed in 13 studies and the recurrence ranged from 0 to 48% in different treatment methods. Conclusion: Due to the high recurrence of this disease, it is suggested that long term follow up be considered after treatment to reduce recurrence. Also it is recommended that the treatment method be selected carefully. Decision on the treatment should be made considering age, tumor size, and the site of involvement in order to reduce the economic and psychological burden of the disease